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[tntryn]

Anyone know what a modified peptide is? I sent mine out for testing and it came back with 99.7% purity, but the molecular weight didn’t match. The lab told me it’s a modified peptide, not a pure one.

 

[tntryn]

Anyone know what a modified peptide is? I sent mine out for testing and it came back with 99.7% purity, but the molecular weight didn’t match. The lab told me it’s a modified peptide, not a pure one.

I got the raw material from HK and did the reconstitution myself before sending it out for testing. I’m not sure if the issue is with the raw material or something I did during the process. Anyone here with lab experience who can help me figure this out?

 

[Jack]

I got the raw material from HK and did the reconstitution myself before sending it out for testing. I’m not sure if the issue is with the raw material or something I did during the process. Anyone here with lab experience who can help me figure this out?

Hey! This is Jack.


Sorry for the late reply — our research team was off over the weekend, and I just got off the phone with them a moment ago.


To answer your question: the peptides like Reta and Tirz from our side are slightly modified with additional stabilizing molecules. This helps improve their overall stability and keeps the activity from degrading over time — especially for research-focused applications. Of course, these are strictly for research use only.


As for the slow dissolution and bubbling during reconstitution — based on what you described, the issue most likely comes from steps during filtration or freeze-drying. It could be a matter of vacuum pressure, residual moisture, or micro-particle presence introduced during handling.


Our researchers will put together a proper explanation document tomorrow, and I’ll make sure to send it your way once it’s ready.


Appreciate you bringing this up!