Paul Montalbano
New member
Who has used this product?
At what dose?
Where you happy and what did you notice?
At what dose?
Where you happy and what did you notice?
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Dosing NAD+
- Thread starter Paul Montalbano
- Start date
Try AI, this is what I got from grok, lol.
I am not a doctor; please consult one before starting NAD+ supplementation or therapy. Dosing for NAD+ varies based on the method of administration, individual health, age, and goals. Below is a general overview based on available research, but you should always consult a healthcare professional to determine the appropriate dose for your needs.
Oral NAD+ Precursors
NAD+ precursors like Nicotinamide Riboside (NR), Nicotinamide Mononucleotide (NMN), and Nicotinamide (NAM) are commonly used to boost NAD+ levels. Typical dosages from studies include:
Nicotinamide Riboside (NR): 250–500 mg per day, with some studies exploring up to 1,000 mg daily. Safe and effective for increasing NAD+ levels.
Nicotinamide Mononucleotide (NMN): 250–900 mg per day, with studies showing benefits at these doses for blood NAD+ concentration.
Nicotinamide (NAM): Up to 3,000 mg per day is well-tolerated, with 900 mg significantly increasing NAD+ levels.
Niacin: 15 mg daily from food or supplements can meet NAD+ needs, but high doses (500 mg or more) may cause side effects like flushing.
Notes:
Oral supplements may have lower bioavailability due to digestion, so precursors like NR or NMN are preferred over NAD+ itself.
Doses are often split (e.g., 250 mg twice daily) for better absorption.
Start with a lower dose (e.g., 100–250 mg) and gradually increase to assess tolerance.
NAD+ Injections
Subcutaneous or intramuscular NAD+ injections are used for more direct delivery. Typical protocols include:
Starting Dose: 50 mg (0.5 mL) once weekly for 4 weeks, increasing to 100 mg weekly if tolerated. Maximum dose is typically 100 mg weekly.
Alternative Protocols: Some start with 25–50 mg 2–3 times per week, titrating up to 0.5 mL (50 mg) 2–3 times weekly.
Cognitive or Addiction Protocols: 5–10 mg daily or 100–200 mg per injection, often over several weeks.
Notes:
Injections are typically administered in the abdomen or upper arm, with sites rotated to avoid irritation.
Some users report starting with micro-doses (e.g., 5 mg twice daily) to minimize side effects.
NAD+ IV Therapy
Intravenous NAD+ therapy delivers higher doses directly into the bloodstream, often for anti-aging, addiction recovery, or cognitive enhancement. Common protocols include:
Standard Dose: 500–1,000 mg per session, administered over 2–4 hours to minimize side effects like nausea or rapid heartbeat.
Loading Protocol: 1,500 mg over 7–10 days (e.g., 250 mg, 500 mg, 500 mg, 250 mg on different days), followed by maintenance doses of 250 mg weekly or monthly.
Addiction Recovery: 500–1,000 mg daily for 4 days, then twice weekly for a month, and maintenance doses every 2 months.
Notes:
IV therapy requires professional administration and slow drip rates (e.g., ≤35 drops per minute) to avoid discomfort.
Higher doses (up to 1,500 mg) may cause mild side effects like flushing or nausea.
NAD+ Nasal Sprays or Peptides
Nasal Spray: Typically 30 mg per spray, once daily.
NAD+ Peptides: 100–500 micrograms per day, used experimentally under medical supervision.
Key Considerations
Individual Factors: Age, health status, lifestyle (e.g., stress, diet, sleep), and goals (e.g., energy, anti-aging, addiction recovery) influence dosing. Older individuals or those with NAD+ depletion may need higher doses.
Safety: NAD+ is generally safe at recommended doses (<2,000 mg/day for IV). Mild side effects include nausea, headache, or flushing, especially at higher doses.
Personalization: An intracellular NAD+ test can help determine baseline levels and optimal dosing.
Contraindications: Avoid NAD+ if you have severe liver/renal issues, cardiovascular disease, or a history of cancer without medical clearance.
Consult a Professional: Dosing should be tailored by a healthcare provider, especially for injections or IV therapy, to avoid interactions (e.g., with antidepressants or insulin).
Practical Tips
Timing: Take oral supplements in the morning to avoid sleep disruption. Injections/IVs are often timed before exercise or in the morning for energy.
Storage: Refrigerate NAD+ vials and discard after 30 days (opened) or 12 months (unopened).
Titration: Start low and increase gradually to monitor tolerance.
For precise dosing, consult a healthcare provider familiar with NAD+ therapy, ideally with baseline testing. If you’re considering a specific protocol (e.g., IV vs. oral), let me know, and I can provide more tailored guidance
I am not a doctor; please consult one before starting NAD+ supplementation or therapy. Dosing for NAD+ varies based on the method of administration, individual health, age, and goals. Below is a general overview based on available research, but you should always consult a healthcare professional to determine the appropriate dose for your needs.
Oral NAD+ Precursors
NAD+ precursors like Nicotinamide Riboside (NR), Nicotinamide Mononucleotide (NMN), and Nicotinamide (NAM) are commonly used to boost NAD+ levels. Typical dosages from studies include:
Nicotinamide Riboside (NR): 250–500 mg per day, with some studies exploring up to 1,000 mg daily. Safe and effective for increasing NAD+ levels.
Nicotinamide Mononucleotide (NMN): 250–900 mg per day, with studies showing benefits at these doses for blood NAD+ concentration.
Nicotinamide (NAM): Up to 3,000 mg per day is well-tolerated, with 900 mg significantly increasing NAD+ levels.
Niacin: 15 mg daily from food or supplements can meet NAD+ needs, but high doses (500 mg or more) may cause side effects like flushing.
Notes:
Oral supplements may have lower bioavailability due to digestion, so precursors like NR or NMN are preferred over NAD+ itself.
Doses are often split (e.g., 250 mg twice daily) for better absorption.
Start with a lower dose (e.g., 100–250 mg) and gradually increase to assess tolerance.
NAD+ Injections
Subcutaneous or intramuscular NAD+ injections are used for more direct delivery. Typical protocols include:
Starting Dose: 50 mg (0.5 mL) once weekly for 4 weeks, increasing to 100 mg weekly if tolerated. Maximum dose is typically 100 mg weekly.
Alternative Protocols: Some start with 25–50 mg 2–3 times per week, titrating up to 0.5 mL (50 mg) 2–3 times weekly.
Cognitive or Addiction Protocols: 5–10 mg daily or 100–200 mg per injection, often over several weeks.
Notes:
Injections are typically administered in the abdomen or upper arm, with sites rotated to avoid irritation.
Some users report starting with micro-doses (e.g., 5 mg twice daily) to minimize side effects.
NAD+ IV Therapy
Intravenous NAD+ therapy delivers higher doses directly into the bloodstream, often for anti-aging, addiction recovery, or cognitive enhancement. Common protocols include:
Standard Dose: 500–1,000 mg per session, administered over 2–4 hours to minimize side effects like nausea or rapid heartbeat.
Loading Protocol: 1,500 mg over 7–10 days (e.g., 250 mg, 500 mg, 500 mg, 250 mg on different days), followed by maintenance doses of 250 mg weekly or monthly.
Addiction Recovery: 500–1,000 mg daily for 4 days, then twice weekly for a month, and maintenance doses every 2 months.
Notes:
IV therapy requires professional administration and slow drip rates (e.g., ≤35 drops per minute) to avoid discomfort.
Higher doses (up to 1,500 mg) may cause mild side effects like flushing or nausea.
NAD+ Nasal Sprays or Peptides
Nasal Spray: Typically 30 mg per spray, once daily.
NAD+ Peptides: 100–500 micrograms per day, used experimentally under medical supervision.
Key Considerations
Individual Factors: Age, health status, lifestyle (e.g., stress, diet, sleep), and goals (e.g., energy, anti-aging, addiction recovery) influence dosing. Older individuals or those with NAD+ depletion may need higher doses.
Safety: NAD+ is generally safe at recommended doses (<2,000 mg/day for IV). Mild side effects include nausea, headache, or flushing, especially at higher doses.
Personalization: An intracellular NAD+ test can help determine baseline levels and optimal dosing.
Contraindications: Avoid NAD+ if you have severe liver/renal issues, cardiovascular disease, or a history of cancer without medical clearance.
Consult a Professional: Dosing should be tailored by a healthcare provider, especially for injections or IV therapy, to avoid interactions (e.g., with antidepressants or insulin).
Practical Tips
Timing: Take oral supplements in the morning to avoid sleep disruption. Injections/IVs are often timed before exercise or in the morning for energy.
Storage: Refrigerate NAD+ vials and discard after 30 days (opened) or 12 months (unopened).
Titration: Start low and increase gradually to monitor tolerance.
For precise dosing, consult a healthcare provider familiar with NAD+ therapy, ideally with baseline testing. If you’re considering a specific protocol (e.g., IV vs. oral), let me know, and I can provide more tailored guidance
Don't you ever think it will be risky to use AI on dosing, lolTry AI, this is what I got from grok, lol.
I am not a doctor; please consult one before starting NAD+ supplementation or therapy. Dosing for NAD+ varies based on the method of administration, individual health, age, and goals. Below is a general overview based on available research, but you should always consult a healthcare professional to determine the appropriate dose for your needs.
Oral NAD+ Precursors
NAD+ precursors like Nicotinamide Riboside (NR), Nicotinamide Mononucleotide (NMN), and Nicotinamide (NAM) are commonly used to boost NAD+ levels. Typical dosages from studies include:
Nicotinamide Riboside (NR): 250–500 mg per day, with some studies exploring up to 1,000 mg daily. Safe and effective for increasing NAD+ levels.
Nicotinamide Mononucleotide (NMN): 250–900 mg per day, with studies showing benefits at these doses for blood NAD+ concentration.
Nicotinamide (NAM): Up to 3,000 mg per day is well-tolerated, with 900 mg significantly increasing NAD+ levels.
Niacin: 15 mg daily from food or supplements can meet NAD+ needs, but high doses (500 mg or more) may cause side effects like flushing.
Notes:
Oral supplements may have lower bioavailability due to digestion, so precursors like NR or NMN are preferred over NAD+ itself.
Doses are often split (e.g., 250 mg twice daily) for better absorption.
Start with a lower dose (e.g., 100–250 mg) and gradually increase to assess tolerance.
NAD+ Injections
Subcutaneous or intramuscular NAD+ injections are used for more direct delivery. Typical protocols include:
Starting Dose: 50 mg (0.5 mL) once weekly for 4 weeks, increasing to 100 mg weekly if tolerated. Maximum dose is typically 100 mg weekly.
Alternative Protocols: Some start with 25–50 mg 2–3 times per week, titrating up to 0.5 mL (50 mg) 2–3 times weekly.
Cognitive or Addiction Protocols: 5–10 mg daily or 100–200 mg per injection, often over several weeks.
Notes:
Injections are typically administered in the abdomen or upper arm, with sites rotated to avoid irritation.
Some users report starting with micro-doses (e.g., 5 mg twice daily) to minimize side effects.
NAD+ IV Therapy
Intravenous NAD+ therapy delivers higher doses directly into the bloodstream, often for anti-aging, addiction recovery, or cognitive enhancement. Common protocols include:
Standard Dose: 500–1,000 mg per session, administered over 2–4 hours to minimize side effects like nausea or rapid heartbeat.
Loading Protocol: 1,500 mg over 7–10 days (e.g., 250 mg, 500 mg, 500 mg, 250 mg on different days), followed by maintenance doses of 250 mg weekly or monthly.
Addiction Recovery: 500–1,000 mg daily for 4 days, then twice weekly for a month, and maintenance doses every 2 months.
Notes:
IV therapy requires professional administration and slow drip rates (e.g., ≤35 drops per minute) to avoid discomfort.
Higher doses (up to 1,500 mg) may cause mild side effects like flushing or nausea.
NAD+ Nasal Sprays or Peptides
Nasal Spray: Typically 30 mg per spray, once daily.
NAD+ Peptides: 100–500 micrograms per day, used experimentally under medical supervision.
Key Considerations
Individual Factors: Age, health status, lifestyle (e.g., stress, diet, sleep), and goals (e.g., energy, anti-aging, addiction recovery) influence dosing. Older individuals or those with NAD+ depletion may need higher doses.
Safety: NAD+ is generally safe at recommended doses (<2,000 mg/day for IV). Mild side effects include nausea, headache, or flushing, especially at higher doses.
Personalization: An intracellular NAD+ test can help determine baseline levels and optimal dosing.
Contraindications: Avoid NAD+ if you have severe liver/renal issues, cardiovascular disease, or a history of cancer without medical clearance.
Consult a Professional: Dosing should be tailored by a healthcare provider, especially for injections or IV therapy, to avoid interactions (e.g., with antidepressants or insulin).
Practical Tips
Timing: Take oral supplements in the morning to avoid sleep disruption. Injections/IVs are often timed before exercise or in the morning for energy.
Storage: Refrigerate NAD+ vials and discard after 30 days (opened) or 12 months (unopened).
Titration: Start low and increase gradually to monitor tolerance.
For precise dosing, consult a healthcare provider familiar with NAD+ therapy, ideally with baseline testing. If you’re considering a specific protocol (e.g., IV vs. oral), let me know, and I can provide more tailored guidance
Yes, AI needs to be fed with a large amount of scientific data and articles before it can become your reliable peptide partner.I would recommend regularly questioning AI when it provides dosing, benefits and risks of substances.
I’ve caught it contradicting itself or sharing erroneous information numerous times.
trueYes, AI needs to be fed with a large amount of scientific data and articles before it can become your reliable peptide partner.
I’ve got the GPT subscription and so far it’s been working great. I just always make sure whenever I ask it for info, it backs it up with legit scientific sources.I would recommend regularly questioning AI when it provides dosing, benefits and risks of substances.
I’ve caught it contradicting itself or sharing erroneous information numerous times.
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